anticancer activity — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2763	Panaxadiol	20(R)-Panaxadiol	Others , HIF/HIF Prolyl-Hydroxylase
	Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.		Others , HIF/HIF Prolyl-Hydroxylase
T2230	Paeoniflorin	Peoniflorin	HSP , COX
	Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.		HSP , COX
T6357	(S)-crizotinib	ent-crizotinib	Apoptosis , DNA/RNA Synthesis , MTH1
	(S)-crizotinib (ent-crizotinib) （IC50 of 72 nM）, an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.		Apoptosis , DNA/RNA Synthesis , MTH1
T14066	9-ING-41		Apoptosis , GSK-3 , Autophagy
	9-ING-41 is a glycogen synthase kinase-3 inhibitor.		Apoptosis , GSK-3 , Autophagy
T0687	Simvastatin	MK-0733,MK 733	Apoptosis , Mitophagy , Ferroptosis , HMG-CoA Reductase , Autophagy
	Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cholesterol, and is also used for the prevention of cardiovasc...
T1488	Procarbazine hydrochloride	NSC-77213 HCl,Procarbazine HCl	DNA Alkylator/Crosslinker , DNA/RNA Synthesis
	Procarbazine hydrochloride (NSC-77213 HCl) is the hydrochloride salt of a methylhydrazine derivative with antineoplastic and mutagenic activities. Although the exact mode of cytotoxicity has not been elucidated, procarba...		DNA Alkylator/Crosslinker , DNA/RNA Synthesis
T28503	Ralitoline	GOE-4942,PD-117818,Ralitolina,CI-946,Ralitolinum
	Ralitoline (Ralitolinum) is an anticonvulsant with anticancer activity and sodium channel blocking activity.
T11562	HIF-2α-IN-3		HIF
	HIF-2α-IN-3 is an allosteric inhibitor of HIF-2α (IC50: 0.4 μM; KD: 1.1 μM) with anticancer activity.		HIF
T68159	Tetrazolast		Antifungal
	Tetrazolast has anticancer activity and may have antifungal activity.		Antifungal
T70086	EPZ033294		Others
	EPZ033294 has potential anticancer and antiproliferative activity.		Others
T15168	DRF-1042		Others
	DRF-1042 acts to inhibit DNA topoisomerase I. DRF-1042 displays perfect anticancer activity against a panel of human cancer cell lines including multi-drug resistance (MDR) phenotype.		Others
T60002	DC-S239		Histone Methyltransferase
	DC-S239 (DC-S239) is a selective inhibitor of histone methyltransferase SETD7 (IC50 = 4.59 μM) with anticancer activity.		Histone Methyltransferase
T12682	Emzadirib	CYT-0851,RAD51-IN-2	DNA/RNA Synthesis
	Emzadirib (RAD51-IN-2) is a potent RAD51 inhibitor with potential anticancer activity for the study of DNA damage repair.		DNA/RNA Synthesis
T13905	Stilbamidine	Ba 2652,Stilbamidin	Antifungal
	Stilbamidine (Ba 2652) has antifungal and anticancer activity and can be used to study multiple myeloma and bladder migratory cell carcinoma.		Antifungal
T35300	Zeniplatin	Zeniplatinum	Others
	Zeniplatin (Zeniplatinum) is a new cisplatin complex with anticancer activity for the treatment of metastatic melanoma and kidney cancer.		Others
T20890	Alvespimycin	17-DMAG,KOS1022,KOS 1022,KOS-1022	HSP
	Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding to Hsp90.		HSP
T60967	Atg4B-IN-2		Phospholipase , Autophagy
	Atg4B-IN-2 is a potent and selective Atg4B inhibitor with anticancer activity that inhibits the activity of Atg4B and PLA2.Atg4B-IN-2 resists the anticancer activity of anti-desiccation-resistant prostate cancer drugs th...		Phospholipase , Autophagy
T78210	STC-15	STC15	Others
	STC-15 is an orally active and potent METTL3 inhibitor with anticancer activity that inhibits cancer growth and induces anticancer immunity.		Others
T15390	Glufosfamide	D 19575,Glucosylifosfamide mustard	Others
	Glufosfamide is a novel oxazolophosphamide compound with anticancer activity for the study of advanced non-small cell lung cancer.		Others
T8668	HM03		HSP
	HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.		HSP